Research library

Retatrutide, developer code LY3437943, is a synthetic peptide characterized as an agonist at the GIP, GLP-1 and glucagon receptors. It is investigational and not approved for any use.

Identity data, as listed on the product page: CAS number 2381089-83-2, molecular formula C221H342N46O68, molecular weight 4731.30 g/mol. It is supplied as a lyophilized powder in a sealed vial.

How it is identified. Identity is confirmed per lot by mass spectrometry, and purity is measured per lot by HPLC. Both results are reported on the lot certificate of analysis, which is linked from the product page.

Regulatory status. Investigational compound. Retatrutide is in clinical trials and is not approved by the FDA or any other regulator for any use. This material is not a drug, supplement, food or cosmetic and has not been evaluated by the FDA. Sold for laboratory research only.

Product and lot number. The product name says what was tested. The lot number says which batch it came from, and it is the same number printed on the vial label. A certificate applies only to the lot it names.

Test date. The date the laboratory ran the analysis, sometimes shown alongside the date the sample was received and the date the report was issued. It tells you how current the result is.

Testing laboratory. The name and address of the laboratory that did the work. On Prime Core Dynamics certificates this is an independent third-party laboratory, not the supplier.

HPLC purity. A percentage from high-performance liquid chromatography. It states what share of the material in the vial is the named compound. The remainder is unidentified peptide-related material or salts. Purity is a measure of composition; it is not a statement of potency.

Mass spectrometry identity. The observed mass of the material, compared with the mass expected for the named molecule. When the two agree within the method's tolerance, the certificate reports the identity as confirmed. This is what establishes that the vial contains the molecule on the label.

Net content. The measured amount of the compound in the vial, in milligrams, set against the amount stated on the label, the label claim. It is often expressed as a percentage of label. On a blend, each component is listed with its own measured amount.

Analyst signature. The name and title of the person at the laboratory who approved the report. It is the laboratory taking responsibility for the numbers above it.

Matching the vial to the certificate. Find the lot number on the vial label. Open the certificate linked from the product page, or the COA library on primecoredynamics.com, and check that the lot number on the certificate is the same. If the two differ, the certificate does not describe the vial in hand.

HPLC. High-performance liquid chromatography, an analytical method that separates the components of a sample as it passes through a packed column under pressure. On a certificate it is the method behind the purity percentage.

Mass spectrometry. An analytical method that measures the mass-to-charge ratio of ionized molecules. Comparing the observed mass with the expected mass is how the identity of a compound is confirmed.

Lyophilized. Freeze-dried. The material was frozen and the water removed under vacuum, leaving a dry powder in the sealed vial.

CAS number. A unique numeric identifier assigned to a chemical substance by the Chemical Abstracts Service. It identifies one substance regardless of the names used for it.

Molecular formula. The count of each kind of atom in one molecule, written with element symbols, for example C21H27N7O14P2 for NAD+.

Molecular weight. The mass of one mole of the molecule, in grams per mole, calculated from the molecular formula.

Lot number. The identifier for one production batch. It links the vial in hand to the certificate of analysis for that batch.

Certificate of analysis. A laboratory report for one lot that states what was tested, the methods, the results and who approved them.

Reference standard. A material of established identity and purity against which other samples are compared in an analytical method.

Research use only. A labeling category for materials supplied for laboratory investigation. It means the material is not offered as a drug, supplement, food, cosmetic or diagnostic and is not for human or veterinary use.